The E-cadherin (CDH1) -C160A polymorphism and colorectal cancer susceptibility: a meta-analysis.

@article{Geng2012TheE,
  title={The E-cadherin (CDH1) -C160A polymorphism and colorectal cancer susceptibility: a meta-analysis.},
  author={Peiliang Geng and Yuying Chen and Juanjuan Ou and Xiaoling Yin and Rina Sa and Houjie Liang},
  journal={DNA and cell biology},
  year={2012},
  volume={31 6},
  pages={1070-7}
}
E-cadherin, encoded by the CDH1 gene, involves in invasion and metastasis of cancer cells. CDH1 -C160A polymorphism was shown to contribute to genetic susceptibility to colorectal cancer (CRC). However, the results from different studies remain controversial. This study was conducted to further explore the association between CDH1 -C160A genetic polymorphism and CRC susceptibility by means of a meta-analysis. A comprehensive literature search was conducted to identify all case-control studies… CONTINUE READING