The Dynamics of Platelet Activation during the Progression of Streptococcal Sepsis

@inproceedings{Hurley2016TheDO,
  title={The Dynamics of Platelet Activation during the Progression of Streptococcal Sepsis},
  author={Sinead M. Hurley and Nataliya Lutay and B. I. Holmqvist and Oonagh Shannon},
  booktitle={PloS one},
  year={2016}
}
Platelets contribute to inflammation however, the role of platelet activation during the pathophysiological response to invasive bacterial infection and sepsis is not clear. Herein, we have investigated platelet activation in a mouse model of invasive Streptococcus pyogenes infection at 5, 12, and 18 hours post infection and correlated this to parameters of infection. The platelet population in ex-vivo blood samples showed no increased integrin activation or surface presentation of CD62P… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 32 references

Plate - let and endothelial cell Pselectin are required for host defense against Klebsiella pneumoniaeinduced pneumosepsis

SF deStoppelaar, C Van’tVeer, +3 authors Tanck MWT
J Thromb Haemost • 2015

The role of platelet MyD 88 in host response during gram - negative sepsis

SF deStoppelaar, Claushuis TAM, +3 authors C vantVeer
J Thromb Haemost • 2015

Thrombocyto - penia and outcome in critically ill patients with bloodstream infection

DM Vandijck, S Blot, +3 authors JM Decruyenaere
Heart and Lung The Journal of Acute and Critical Care . Elsevier Inc • 2010

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