The Dynamics of Bacterial Infection , Innate Immune Response , and Antibiotic Treatment

@inproceedings{Imran2006TheDO,
  title={The Dynamics of Bacterial Infection , Innate Immune Response , and Antibiotic Treatment},
  author={Mudassar Imran and Hal L. Smith},
  year={2006}
}
We develop a simple mathematical model of a bacterial colonization of host tissue which takes account of nutrient availability and innate immune response. The model features an infection-free state which is locally but not globally attracting implying that a super-threshold bacterial inoculum is required for successful colonization and tissue infection. A subset B of the domain of attraction of the disease-free state is explicitly identified. The dynamics of antibiotic treatment of the… CONTINUE READING

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