The Drosophila telomere-capping protein Verrocchio binds single-stranded DNA and protects telomeres from DNA damage response

@inproceedings{Cicconi2017TheDT,
  title={The Drosophila telomere-capping protein Verrocchio binds single-stranded DNA and protects telomeres from DNA damage response},
  author={Alessandro Cicconi and Emanuela Micheli and Fiammetta Vern{\`i} and Alison Jackson and Ana Citlali Gradilla and Francesca Cipressa and Domenico Raimondo and Giuseppe Bosso and James G Wakefield and Laura Ciapponi and Giovanni Cenci and Maurizio Gatti and Stefano Cacchione and Grazia Daniela Raffa},
  booktitle={Nucleic acids research},
  year={2017}
}
Drosophila telomeres are sequence-independent structures maintained by transposition to chromosome ends of three specialized retroelements rather than by telomerase activity. Fly telomeres are protected by the terminin complex that includes the HOAP, HipHop, Moi and Ver proteins. These are fast evolving, non-conserved proteins that localize and function exclusively at telomeres, protecting them from fusion events. We have previously suggested that terminin is the functional analogue of… CONTINUE READING
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