The Drosophila suppressor of sable protein binds to RNA and associates with a subset of polytene chromosome bands.

@article{Murray1997TheDS,
  title={The Drosophila suppressor of sable protein binds to RNA and associates with a subset of polytene chromosome bands.},
  author={Marion Murray and Michael A Turnage and Kenneth J. Williamson and W R Steinhauer and Lillie L. Searles},
  journal={Molecular and cellular biology},
  year={1997},
  volume={17 4},
  pages={2291-300}
}
Mutations of the Drosophila melanogaster suppressor of sable [su(s)] gene, which encodes a 150-kDa nuclear protein [Su(s)], increase the accumulation of specific transcripts in a manner that is not well understood but that appears to involve pre-mRNA processing. Here, we report biochemical analysis of purified, recombinant Su(s) [rSu(s)] expressed in baculovirus and in Escherichia coli as maltose binding protein (MBP) fusions and immunocytochemical analysis of endogenous Su(s). This work has… CONTINUE READING

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