The Drosophila snr1 and brm proteins are related to yeast SWI/SNF proteins and are components of a large protein complex.

@article{Dingwall1995TheDS,
  title={The Drosophila snr1 and brm proteins are related to yeast SWI/SNF proteins and are components of a large protein complex.},
  author={Andrew K. Dingwall and S J Beek and C. Michael McCallum and John W. Tamkun and Ganjam V. Kalpana and Stephen P Goff and Matthew P Scott},
  journal={Molecular biology of the cell},
  year={1995},
  volume={6 7},
  pages={777-91}
}
During most of Drosophila development the regulation of homeotic gene transcription is controlled by two groups of regulatory genes, the trithorax group of activators and the Polycomb group of repressors. brahma (brm), a member of the trithorax group, encodes a protein related to the yeast SWI2/SNF2 protein, a subunit of a protein complex that assists sequence-specific activator proteins by alleviating the repressive effects of chromatin. To learn more about the molecular mechanisms underlying… CONTINUE READING
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