The Drosophila muscle LIM protein, Mlp84B, cooperates with D-titin to maintain muscle structural integrity.

@article{Clark2007TheDM,
  title={The Drosophila muscle LIM protein, Mlp84B, cooperates with D-titin to maintain muscle structural integrity.},
  author={Kathleen A. Clark and Jennifer M Bland and Mary C Beckerle},
  journal={Journal of cell science},
  year={2007},
  volume={120 Pt 12},
  pages={2066-77}
}
Muscle LIM protein (MLP) is a cytoskeletal LIM-only protein expressed in striated muscle. Mutations in human MLP are associated with cardiomyopathy; however, the molecular mechanism by which MLP functions is not established. A Drosophila MLP homolog, mlp84B, displays many of the same features as the vertebrate protein, illustrating the utility of the fly for the study of MLP function. Animals lacking Mlp84B develop into larvae with a morphologically intact musculature, but the mutants arrest… CONTINUE READING
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