The Drosophila couch potato gene: an essential gene required for normal adult behavior.

@article{Bellen1992TheDC,
  title={The Drosophila couch potato gene: an essential gene required for normal adult behavior.},
  author={Hugo J. Bellen and Harald E. F. Vaessin and Ethan Bier and Alex L Kolodkin and Diana D'Evelyn and S Kooyer and Yuh Nung Jan},
  journal={Genetics},
  year={1992},
  volume={131 2},
  pages={
          365-75
        }
}
Through enhancer detection screens we have isolated 14 insertions in an essential gene that is expressed in embryonic sensory mother cells (SMC), in most cells of the mature embryonic peripheral nervous system (PNS), and in glial cells of the PNS and the central nervous system (CNS). Embryos homozygote for amorphic alleles die, but show no obvious defects in their cuticle, PNS or CNS. The gene has been named couch potato (cpo) because several insertional alleles alter adult behavior. Homozygous… CONTINUE READING

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