The Drosophila acetylcholine receptor subunit D alpha5 is part of an alpha-bungarotoxin binding acetylcholine receptor.

@article{Wu2005TheDA,
  title={The Drosophila acetylcholine receptor subunit D alpha5 is part of an alpha-bungarotoxin binding acetylcholine receptor.},
  author={Peipei Wu and Dongdong Ma and Marek Pierzchala and Jun Wu and Lee-Chuan Yang and Xiaoping Mai and Xiaoying Chang and Thomas Schmidt-Glenewinkel},
  journal={The Journal of biological chemistry},
  year={2005},
  volume={280 22},
  pages={20987-94}
}
The central nervous system of Drosophila melanogaster contains an alpha-bungarotoxin-binding protein with the properties expected of a nicotinic acetylcholine receptor. This protein was purified 5800-fold from membranes prepared from Drosophila heads. The protein was solubilized with 1% Triton X-100 and 0.5 M sodium chloride and then purified using an alpha-cobratoxin column followed by a lentil lectin affinity column. The purified protein had a specific activity of 3.9 micromol of 125I-alpha… CONTINUE READING