The Drosophila Tumorous lethal hematopoietic oncogene is a dominant mutation in the hopscotch locus

@article{Hanratty1993TheDT,
  title={The Drosophila Tumorous lethal hematopoietic oncogene is a dominant mutation in the hopscotch locus},
  author={William P. Hanratty and Charles R. Dearolf},
  journal={Molecular and General Genetics MGG},
  year={1993},
  volume={238},
  pages={33-37}
}
The Drosophila Tumorous-lethal (Tum-l) mutation acts as an activated oncogene, causing hematopoietic neoplasms, overproliferation, and premature differentiation. Tum-l is a dominant mutation in the hopscotch (hop) locus, which is required for cell division and for proper embryonic segmentation. The Tum-l temperature-sensitive period for melanotic tumor formation includes most of larval and pupal development.