The Drosophila Standard Brain

@article{Rein2002TheDS,
  title={The Drosophila Standard Brain},
  author={Karlheinz Rein and Malte Z{\"o}ckler and Michael T. Mader and Cornelia Gr{\"u}bel and Martin Heisenberg},
  journal={Current Biology},
  year={2002},
  volume={12},
  pages={227-231}
}

Figures from this paper

Three-Dimensional Atlases of Insect Brains
TLDR
In this review, digital, three-dimensional atlases were generated to provide geometrical as well as conceptual reference systems for the brains of several insect species and the key problems that must be overcome and the solutions found are highlighted.
Combining genome-scale Drosophila 3D neuroanatomical data by bridging template brains
TLDR
This work constructs bridging registrations between template brains accounting for the vast majority of Drosophila melanogaster 3D neuroanatomical data and solves the related problem of mapping data between the left and right brain hemispheres via the construction of mirroring registrations.
One brain fits all
  • W. Wells
  • Biology
    The Journal of Cell Biology
  • 2002
TLDR
Martin Heisenberg is attempting to move fly neurobiology from the qualitative to the quantitative, and has constructed a Drosophila standard brain, which he hopes that researchers will contribute to the model by adding expression patterns of their favorite genes and will use the model to characterize mutants.
Average shape standard atlas for the adult Drosophila ventral nerve cord
TLDR
A standard average shape atlas for the ventral nerve cord (VNC) of Drosophila melanogaster is established, which allows for the registration of morphological, developmental, and genetic data into one quantitative 3D reference system.
An unbiased template of the Drosophila brain and ventral nerve cord
TLDR
This work created high-resolution templates of the Drosophila brain and ventral nerve cord using the best-available technologies for imaging, artifact correction, stitching, and template construction using groupwise registration and demonstrates that theirs enables more accurate registration with fewer local deformations in shorter time.
An unbiased template of the Drosophila brain and ventral nerve cord.
TLDR
This work created high-resolution templates of the Drosophila brain and ventral nerve cord using the best-available technologies for imaging, artifact correction, stitching, and template construction using groupwise registration and demonstrates that theirs enables more accurate registration with fewer local deformations in shorter time.
A Statistically Representative Atlas for Mapping Neuronal Circuits in the Drosophila Adult Brain
TLDR
This work objectively evaluated the performance of different strategies for building adult Drosophila brain templates and atlases and used state-of-the-art registration algorithms to generate a new group-wise inter-sex atlas that outperformed existing solutions for automated registration and annotation of expression patterns.
The Virtual Insect Brain protocol: creating and comparing standardized neuroanatomy
TLDR
The Virtual Insect Brain protocol is developed for the standardization of Drosophila neuroanatomy and provides volumetry of brain regions and helps to characterize the phenotypes of brain structure mutants.
Developing a Stereotypical Drosophila Brain Atlas
TLDR
The main contribution and novelty of this study is to determine the average 3D brain shape based on the isosurface suggested by the zero-crossings of a 3D accumulative signed distance map.
Computational neuroanatomy of the central complex of Drosophila melanogaster
TLDR
The aim of this project is to generate accurate quantitative neuroanatomy of the central complex in the fruit fly Drosophila melanogaster by annotating and registering brains to produce central complex template images and also files that accurately represent the possible central complex connectivity apparent in these images.
...
...

References

SHOWING 1-10 OF 27 REFERENCES
Isolation of Anatomical Brain Mutants of Drosophila by Histological Means
TLDR
A simple method has been designed which allows to process up to 20 identifiable flies as a single preparation in a standard histology routine and some of the mutants may prove to be useful in anatomical, physiological or genetic brain research.
Maps of the Brain
TLDR
It is described how brain atlases, and the computational tools that align new datasets with them, facilitate comparison of brain data across experiments, laboratories, and from different imaging devices to identify general patterns of structural and functional variation in human populations.
A higher control center of locomotor behavior in the Drosophila brain
  • R. StraussM. Heisenberg
  • Biology, Psychology
    The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 1993
TLDR
Walking in 15 Drosophila mutant strains belonging to eight independent X-linked genes that affect the structure of the central complex is examined, finding that declining walking activity is not an unspecific side effect of structural brain defects, as steady walking is observed in structural mutants of the visual system and mushroom bodies.
Three‐dimensional reconstruction of the antennal lobe in Drosophila melanogaster
TLDR
Glomerular variability observed occasionally between males and females is in the same range as between individuals of the same sex, suggesting the lack of a significant sexual dimorphism in the glomerular pattern.
Behavior‐dependent activity labeling in the central complex of Drosophila during controlled visual stimulation
TLDR
The labeling patterns support earlier notions that the central complex is involved in the initiation and organization of behavior and that it integrates visual data of the two brain hemispheres.
Creating Virtual Insect Brains with Amira
TLDR
A standard brain model for drosophila and honey bee brains is created and recently published and serves as a user's guide for scientist who want to reproduce the results for differerent species or mutants.
Principles of visual motion detection
Expression of Drosophila mushroom body mutations in alternative genetic backgrounds: a case study of the mushroom body miniature gene (mbm).
TLDR
It is proposed that polymorphic gene interactions (in addition to ontogenetic factors) determine MB size and, concomitantly, the ability to recognize and learn odors.
A digital three-dimensional atlas of the honeybee antennal lobe based on optical sections acquired by confocal microscopy
TLDR
A digital atlas of the glomeruli in the antennal lobe of the honeybee, Apis mellifera, accessible to the scientific community via the Internet is presented, a step towards interactive and freely accessible databases of animal brains.
...
...