The Drosophila PNG kinase complex regulates the translation of cyclin B.

@article{Vardy2007TheDP,
  title={The Drosophila PNG kinase complex regulates the translation of cyclin B.},
  author={Leah Vardy and Terry L Orr-Weaver},
  journal={Developmental cell},
  year={2007},
  volume={12 1},
  pages={157-66}
}
The Drosophila PAN GU (PNG) kinase complex regulates the developmental translation of cyclin B. cyclin B mRNA becomes unmasked during oogenesis independent of PNG activity, but PNG is required for translation from egg activation. We find that although polyadenylation of cyclin B augments translation, it is not essential, and a fully elongated poly(A) is not required for translation to proceed. In fact, changes in poly(A) tail length are not sufficient to account for PNG-mediated control of… CONTINUE READING

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