The DnaA Tale

@inproceedings{Hansen2018TheDT,
  title={The DnaA Tale},
  author={Flemming Gundorph Hansen and Tove Atlung},
  booktitle={Front. Microbiol.},
  year={2018}
}
More than 50 years have passed since the presentation of the Replicon Model which states that a positively acting initiator interacts with a specific site on a circular chromosome molecule to initiate DNA replication. Since then, the origin of chromosome replication, oriC, has been determined as a specific region that carries sequences required for binding of positively acting initiator proteins, DnaA-boxes and DnaA proteins, respectively. In this review we will give a historical overview of… CONTINUE READING

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