The Dishevelled-associating protein Daple controls the non-canonical Wnt/Rac pathway and cell motility.

@article{IshidaTakagishi2012TheDP,
  title={The Dishevelled-associating protein Daple controls the non-canonical Wnt/Rac pathway and cell motility.},
  author={Maki Ishida-Takagishi and Atsushi Enomoto and Naoya Asai and Kaori Ushida and Takashi Watanabe and Takahiko Hashimoto and Takuya Kato and Liang Weng and Shinji Matsumoto and Masato Asai and Yoshiki Murakumo and Kozo Kaibuchi and Akira Kikuchi and Masahide Takahashi},
  journal={Nature communications},
  year={2012},
  volume={3},
  pages={859}
}
Dishevelled is the common mediator of canonical and non-canonical Wnt signalling pathways, which are important for embryonic development, tissue maintenance and cancer progression. In the non-canonical Wnt signalling pathway, the Rho family of small GTPases acting downstream of Dishevelled has essential roles in cell migration. The mechanisms by which the… CONTINUE READING