The Discovery of Vitamin C

  title={The Discovery of Vitamin C},
  author={Kenneth J. Carpenter},
  journal={Annals of Nutrition and Metabolism},
  pages={259 - 264}
  • K. Carpenter
  • Published 1 November 2012
  • Medicine
  • Annals of Nutrition and Metabolism
The term ‘scurvy’ for the disease resulting from prolonged vitamin C deficiency had origins in ‘scorbutus’ (Latin), ‘scorbut’ (French), and ‘Skorbut’ (German). Scurvy was a common problem in the world’s navies and is estimated to have affected 2 million sailors. In 1747, James Lind conducted a trial of six different treatments for 12 sailors with scurvy: only oranges and lemons were effective in treating scurvy. Scurvy also occurred on land, as many cases occurred with the ‘great potato famine… 

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One hundred years ago, in 1912, the Polish-American scientist Casimir Funk coined the term ‘vitamine’ to describe a group of bioactive substances the authors now know to be essential for human health – a pivotal discovery that has contributed to a century of innovative research and improved health.

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Hexuronic Acid as the Antiscorbutic Factor

AT the wish and by the courtesy of Prof. A. Szent-Györgyi, I arranged to examine in my laboratory the ‘hexuronic acid’ which he isolated while working in the Biochemical Laboratory, Cambridge. At the

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Experimental Studies Relating to Ship-beri-beri and Scurvy. II. On the Etiology of Scurvy

  • A. Holst
  • Medicine
    Epidemiology and Infection
  • 1907
It is found that guinea-pigs also contract a disease, and that this disease is accompanied by very characteristic changes.

Scurvy produced by a Zen macrobiotic diet.

A woman who embraced a Zen macrobiotic philosophy with its rigid nutritional system was completely bedridden and near death with the classical manifestations of scurvy and severe folic acid and

Hexuronic Acid as the Antiscorbutic Factor

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Observations on the function of peroxidase systems and the chemistry of the adrenal cortex: Description of a new carbohydrate derivative.

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  • A. Garrod
  • Monthly Journal of Medical Science
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