The Discovery of Captopril

@article{Smith2003TheDO,
  title={The Discovery of Captopril},
  author={Charles G. Smith and John Robert Vane},
  journal={The FASEB Journal},
  year={2003},
  volume={17}
}
Over the past few years, and particularly recently, there has been a goodly amount of discussion in the press about the discovery and development of highly successful drugs by the pharmaceutical industry, in which extensive data generated by government-sponsored research is claimed to have played a significant role in the industry’s success. Detailed analysis of these claims (1) has concluded that the concept of major monetary input into such drugs by the government is not justified. Indeed… 

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References

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An assessment of the relationship between the private and public sectors in drug discovery and development of 21 "impact" drugs found that any attempt to measure the relative contribution of the public and private sectors to the research and development (R&D) of therapeutically important drugs is flawed.