The Dictyostelium bZIP transcription factor DimB regulates prestalk-specific gene expression.

@article{Zhukovskaya2006TheDB,
  title={The Dictyostelium bZIP transcription factor DimB regulates prestalk-specific gene expression.},
  author={Natasha V. Zhukovskaya and Masashi Fukuzawa and Yoko Yamada and Tsuyoshi Araki and Jeffrey G. Williams},
  journal={Development},
  year={2006},
  volume={133 3},
  pages={439-48}
}
The ecmA gene is specifically expressed in prestalk cells and its transcription is induced by the chlorinated hexaphenone DIF-1. We have purified a novel bZIP transcription factor, DimB, by affinity chromatography on two spatially separated ecmA promoter fragments. Mutagenesis of the cap-site proximal DimB-binding site (the -510 site) greatly decreases ecmA… CONTINUE READING