The Dictyostelium Kinome—Analysis of the Protein Kinases from a Simple Model Organism

  title={The Dictyostelium Kinome—Analysis of the Protein Kinases from a Simple Model Organism},
  author={Jonathan M. Goldberg and Gerard Manning and Allen P Liu and Petra Fey and Karen E. Pilcher and Yanji Xu and Janet L. Smith},
  journal={PLoS Genetics},
  pages={972 - 977}
Dictyostelium discoideum is a widely studied model organism with both unicellular and multicellular forms in its developmental cycle. The Dictyostelium genome encodes 285 predicted protein kinases, similar to the count of the much more advanced Drosophila. It contains members of most kinase classes shared by fungi and metazoans, as well as many previously thought to be metazoan specific, indicating that they have been secondarily lost from the fungal lineage. This includes the entire tyrosine… CONTINUE READING

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