The Development of Drugs against Acanthamoeba Infections.

  title={The Development of Drugs against Acanthamoeba Infections.},
  author={Ruqaiyyah Siddiqui and Yousuf Aqeel and Naveed Ahmed Khan},
  journal={Antimicrobial agents and chemotherapy},
  volume={60 11},
For the past several decades, there has been little improvement in the morbidity and mortality associated with Acanthamoeba keratitis and Acanthamoeba encephalitis, respectively. The discovery of a plethora of antiacanthamoebic compounds has not yielded effective marketed chemotherapeutics. The rate of development of novel antiacanthamoebic chemotherapies of translational value and the lack of interest of the pharmaceutical industry in developing such chemotherapies have been disappointing. On… CONTINUE READING