The Dehydroepiandrosterone And WellNess (DAWN) study: research design and methods.

@article{Mhlen2007TheDA,
  title={The Dehydroepiandrosterone And WellNess (DAWN) study: research design and methods.},
  author={Denise G von M{\"u}hlen and Gail A. Laughlin and Donna Kritz-Silverstein and Elizabeth Barrett-Connor},
  journal={Contemporary clinical trials},
  year={2007},
  volume={28 2},
  pages={153-68}
}
Levels of dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEAS), the major secretory products of the adrenal gland, decline dramatically with age, concurrent with the onset of degenerative changes and chronic diseases associated with aging. Epidemiological evidences in humans and animal studies suggest that DHEA(S) may have cardioprotective, antiobesity, antidiabetic, and immuno-enhancing properties. These observations led to the proposal that restoration of DHEA to young adult levels may have… CONTINUE READING