The Degradation of Mitomycin C Under Various Storage Methods.


PURPOSE To compare the effects of common pharmacy preparation and storage conditions on the stability of mitomycin C (MMC) in solution. METHODS We used C18 reversed-phase high-performance liquid chromatography to determine the stability of 0.4 mg/mL MMC solutions, and liquid chromatography-electrospray ionization-mass spectrometry to identify degradation… (More)
DOI: 10.1097/IJG.0000000000000287