The Default Mode Network in Healthy Aging and Alzheimer's Disease

  title={The Default Mode Network in Healthy Aging and Alzheimer's Disease},
  author={Katell Mevel and Ga{\"e}l Ch{\'e}telat and Francis Eustache and B{\'e}atrice Desgranges},
  booktitle={International journal of Alzheimer's disease},
In the past decade, a "default mode network" (DMN) has been highlighted in neuroimaging studies as a set of brain regions showing increased activity in task-free state compared to cognitively demanding task, and synchronized activity at rest. Changes within this network have been described in healthy aging as well as in Alzheimer's disease (AD) and populations at risk for AD, that is, amnestic Mild Cognitive Impairment (aMCI) patients and APOE-ε4 carriers. This is of particular interest in the… CONTINUE READING

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