The Danish PET/depression project: PET findings in patients with major depression.

@article{Videbech2001TheDP,
  title={The Danish PET/depression project: PET findings in patients with major depression.},
  author={Poul Videbech and Barbara Ravnkilde and Asger Roer Pedersen and Annette Egander and B Landbo and Niels Anton Rasmussen and Flemming Andersen and Hans St\odkilde-J\orgensen and Albert Gjedde and Raben Rosenberg},
  journal={Psychological medicine},
  year={2001},
  volume={31 7},
  pages={1147-58}
}
BACKGROUND It is hypothesized from previous positron emission tomography (PET) studies of patients with major depression that dysfunction of regions of the limbic system and the frontal lobes in close connection with the basal ganglia is involved in the pathophysiology of major depression. METHODS By means of PET and 15O labelled radioactive water we determined an index of the neuronal activity by mapping the cerebral blood flow distribution of 42 unselected in-patients suffering from… CONTINUE READING