The DNA damage response at eroded telomeres and tethering to the nuclear pore complex

Abstract

The ends of linear eukaryotic chromosomes are protected by telomeres, which serve to ensure proper chromosome replication and to prevent spurious recombination at chromosome ends. In this study, we show by single cell analysis that in the absence of telomerase, a single short telomere is sufficient to induce the recruitment of checkpoint and recombination… (More)
DOI: 10.1038/ncb1910

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@article{Khadaroo2009TheDD, title={The DNA damage response at eroded telomeres and tethering to the nuclear pore complex}, author={Basheer Khadaroo and M. Teresa Teixeira and Pierre Luciano and Nadine Eckert-Boulet and Susanne Manuela Germann and Marie Noelle Simon and Irene Gallina and Pauline Abdallah and Eric Gilson and Vincent G{\'e}li and Michael Lisby}, journal={Nature Cell Biology}, year={2009}, volume={11}, pages={980-987} }