The DNA-binding capacity of genetic variants of the bovine STAT5A transcription factor.

@article{Flisikowski2003TheDC,
  title={The DNA-binding capacity of genetic variants of the bovine STAT5A transcription factor.},
  author={Krzysztof Flisikowski and Małgorzata Szymanowska and Lech Zwierzchowski},
  journal={Cellular & molecular biology letters},
  year={2003},
  volume={8 3},
  pages={831-40}
}
The STATs are a family of transcription factors. STAT5A, previously known as MGF, transduces prolactin signals to the milk protein genes. Here, we describe the detection of nucleotide sequence polymorphism in exon 16 of the bovine STAT5A gene, coding for the SH2 domain. SSCP was found in a 281-bp PCR amplified gene fragment, lying between positions 12,525 and 12,806, and encompassing parts of intron 15 and exon 16 of the bovine STAT5A gene (GenBank AJ 237937). Three SSCP patterns (genotypes… CONTINUE READING
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