The DIADEM Metric: Comparing Multiple Reconstructions of the Same Neuron

@article{Gillette2011TheDM,
  title={The DIADEM Metric: Comparing Multiple Reconstructions of the Same Neuron},
  author={Todd A. Gillette and Kerry M. Brown and Giorgio A. Ascoli},
  journal={Neuroinformatics},
  year={2011},
  volume={9},
  pages={233-245}
}
Digital reconstructions of neuronal morphology are used to study neuron function, development, and responses to various conditions. Although many measures exist to analyze differences between neurons, none is particularly suitable to compare the same arborizing structure over time (morphological change) or reconstructed by different people and/or software (morphological error). The metric introduced for the DIADEM (DIgital reconstruction of Axonal and DEndritic Morphology) Challenge quantifies… CONTINUE READING
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