The DAZL family proteins are PABP-binding proteins that regulate translation in germ cells.

@article{Collier2005TheDF,
  title={The DAZL family proteins are PABP-binding proteins that regulate translation in germ cells.},
  author={Brian W. Collier and Barbara Gorgoni and Carolyn J. Loveridge and Howard J. Cooke and Nicola K Gray},
  journal={The EMBO journal},
  year={2005},
  volume={24 14},
  pages={2656-66}
}
DAZL proteins are germ-cell-specific RNA-binding proteins essential for gametogenesis. The precise molecular role of these proteins in germ-cell development remains enigmatic; however, they appear to function in the cytoplasm. In order to directly address the function of vertebrate DAZL proteins, we have used Xenopus laevis oocytes as a model system. Here we demonstrate that members of this family, including Xdazl, mouse Dazl, human DAZL, human DAZ and human BOULE, have the ability to stimulate… CONTINUE READING
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