The D2 dopamine receptor gene: a review of association studies in alcoholism and phenotypes.

@article{Noble1998TheDD,
  title={The D2 dopamine receptor gene: a review of association studies in alcoholism and phenotypes.},
  author={Ernest Pascal Noble},
  journal={Alcohol},
  year={1998},
  volume={16 1},
  pages={33-45}
}
The role of the D2 dopamine receptor (DRD2) gene in alcoholism and other substance use disorders has come under intense investigation since the minor TaqI A (A1) allele of the DRD2 gene was first reported to be associated with alcoholism. In a meta-analysis of 15 US and international studies of European (non-Hispanic) Caucasians, consisting of 1015 alcoholics (more severe and less severe) and 898 controls (unassessed and assessed for alcoholism), alcoholics had a higher prevalence (p < 10(-7… CONTINUE READING

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