The CsoR-like sulfurtransferase repressor (CstR) is a persulfide sensor in Staphylococcus aureus.

@article{Luebke2014TheCS,
  title={The CsoR-like sulfurtransferase repressor (CstR) is a persulfide sensor in Staphylococcus aureus.},
  author={Justin L Luebke and Jiangchuan Shen and Kevin E. Bruce and Thomas E Kehl-Fie and Hui Peng and Eric P Skaar and David P Giedroc},
  journal={Molecular microbiology},
  year={2014},
  volume={94 6},
  pages={1343-60}
}
How cells regulate the bioavailability of utilizable sulfur while mitigating the effects of hydrogen sulfide toxicity is poorly understood. CstR [Copper-sensing operon repressor (CsoR)-like sulfurtransferase repressor] represses the expression of the cst operon encoding a putative sulfide oxidation system in Staphylococcus aureus. Here, we show that the cst operon is strongly and transiently induced by cellular sulfide stress in an acute phase and specific response and that cst-encoded genes… CONTINUE READING
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