The Cry4B toxin of Bacillus thuringiensis subsp. israelensis kills Permethrin-resistant Anopheles gambiae, the principal vector of malaria.

@article{Ibrahim2013TheCT,
  title={The Cry4B toxin of Bacillus thuringiensis subsp. israelensis kills Permethrin-resistant Anopheles gambiae, the principal vector of malaria.},
  author={Mohamed Elgamri A. Ibrahim and Natalya B Griko and Lee A. Bulla},
  journal={Experimental biology and medicine},
  year={2013},
  volume={238 4},
  pages={
          350-9
        }
}
Resurgence of malaria has been attributed, in part, to the development of resistance by Anopheles gambiae, a principal vector of the disease, to various insecticidal compounds such as Permethrin. Permethrin, a neurotoxicant, is widely used to impregnate mosquito nets. An alternative strategy to control mosquitoes is the use of Bacillus thuringiensis subsp. israelensis (Bti) because there is no observable resistance in the field to the bacterium. Bti kills mosquitoes by targeting cadherin… CONTINUE READING
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Cry4B Toxin of Bacillus thuringiensis subsp. israelensis

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