The Critical Role of Polyglutamylation Reductase and Inhibitors of Other Folate-requiring Enzymes : Synergy between Inhibitors of Dihydrofolate in Vitro Super Updated

@inproceedings{Slocum2006TheCR,
  title={The Critical Role of Polyglutamylation Reductase and Inhibitors of Other Folate-requiring Enzymes : Synergy between Inhibitors of Dihydrofolate in Vitro Super Updated},
  author={Harry K. Slocum and L Robert and Charles Jackson and Theodore and J. Boritzki and Youcef and M. Rustum and Muraleedharan G Nair and William and Rossella Greco},
  year={2006}
}
The combined action among polyglutamylatable and nonpolyglutamylatable antifolates, directed against dihydrofolate reducÃ-ase (DHFR), glycinamide ribonucleotide formyltransferase (GARFT), 5-aminoimidazole4-carboxamide ribonucleotide formyltransferase (AICARFT), and thymidylate synthase (TS), in human ileocecal HCT-8 cells was examined in a 96-well plate… CONTINUE READING