The Corynebacterium diphtheriae iron-regulated surface protein HbpA is involved in the utilization of the Hemoglobin-Haptoglobin complex as an iron source.

@article{Lyman2018TheCD,
  title={The Corynebacterium diphtheriae iron-regulated surface protein HbpA is involved in the utilization of the Hemoglobin-Haptoglobin complex as an iron source.},
  author={Lindsey R Lyman and Eric D. Peng and Michael P. Schmitt},
  journal={Journal of bacteriology},
  year={2018}
}
Corynebacterium diphtheriae utilizes various heme-containing proteins, including hemoglobin (Hb) and the hemoglobin-haptoglobin complex (Hb-Hp), as iron sources during growth in iron-depleted environments. The ability to utilize Hb-Hp as an iron source requires the surface anchored proteins HtaA and either ChtA or ChtC. The ability to bind hemin, Hb and Hb-Hp by each of these C. diphtheriae proteins requires the previously characterized Conserved Region (CR) domain. In this study, we identified… CONTINUE READING
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