The Core and Accessory Genomes of Burkholderia pseudomallei: Implications for Human Melioidosis

@article{Sim2008TheCA,
  title={The Core and Accessory Genomes of Burkholderia pseudomallei: Implications for Human Melioidosis},
  author={Siew Hoon Sim and Yiting Yu and Chi Ho Lin and Radha Krishna Murthy Karuturi and Vanaporn Wuthiekanun and Apichai Tuanyok and Hui Hoon Chua and Catherine E. L. Ong and Sivalingam Suppiah Paramalingam and Gladys Tan and Lynn L H Tang and Gary K. Lau and Eng Eong Ooi and Donald Woods and Edward Feil and Sharon J Peacock and Patrick Tan},
  journal={PLoS Pathogens},
  year={2008},
  volume={4},
  pages={421 - 428}
}
Natural isolates of Burkholderia pseudomallei (Bp), the causative agent of melioidosis, can exhibit significant ecological flexibility that is likely reflective of a dynamic genome. Using whole-genome Bp microarrays, we examined patterns of gene presence and absence across 94 South East Asian strains isolated from a variety of clinical, environmental, or… CONTINUE READING

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