The Conversion of Human Prothrombin to Thrombin by Sodium Citrate ANALYSIS OF THE ACTIVATION MIXTURE*

  • GERARD P. LANCHANTIN
  • Published 2003

Abstract

Since the discovery that bovine prothrombin when dissolved in 25% sodium citrate is autocatalytically converted to thrombin (2), several reviews have appeared which summarize the many chemical and biological changes occurring during this transformation (3-5). Recently the findings that poly-L-lysine, as well as a number of polyamino acids, initiates… (More)

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