The Contribution of E2F-Regulated Transcription to Drosophila PCNA Gene Function

Abstract

E2F proteins control cell cycle progression by predominantly acting as either activators or repressors of transcription. How the antagonizing activities of different E2Fs are integrated by cis-acting control regions into a final transcriptional output in an intact animal is not well understood. E2F function is required for normal development in many species… (More)
DOI: 10.1016/S0960-9822(02)01400-8

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