The Complex Interplay between Metabolic Reprogramming and Epigenetic Alterations in Renal Cell Carcinoma

@article{Lameirinhas2019TheCI,
  title={The Complex Interplay between Metabolic Reprogramming and Epigenetic Alterations in Renal Cell Carcinoma},
  author={A. Lameirinhas and Vera Miranda-Gonçalves and R. Henrique and C. Jer{\'o}nimo},
  journal={Genes},
  year={2019},
  volume={10}
}
Renal cell carcinoma (RCC) is the most common malignancy affecting the kidney. Current therapies are mostly curative for localized disease, but do not completely preclude recurrence and metastization. Thus, it is imperative to develop new therapeutic strategies based on RCC biological properties. Presently, metabolic reprograming and epigenetic alterations are recognized cancer hallmarks and their interactions are still in its infancy concerning RCC. In this review, we explore RCC biology… Expand
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References

SHOWING 1-10 OF 167 REFERENCES
Interplay between epigenetics and metabolism in oncogenesis: mechanisms and therapeutic approaches
  • 114
  • Highly Influential
  • PDF
Novel drugs that target the metabolic reprogramming in renal cell cancer
  • 42
Metabolic Signaling to Epigenetic Alterations in Cancer
  • 16
  • PDF
Metabolic features of clear-cell renal cell carcinoma: mechanisms and clinical implications.
  • 48
Metabolic reprogramming in clear cell renal cell carcinoma
  • 99
The epigenetic landscape of renal cancer
  • 60
  • PDF
Metabolic control of epigenetics in cancer
  • 169
Renal Cell Carcinoma Deep Sequencing: Recent Developments
  • 13
...
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2
3
4
5
...