The Comparison of Effectiveness of Various Potential Predictors of Response to Treatment With SSRIs in Patients With Depressive Disorder.

@article{Bares2017TheCO,
  title={The Comparison of Effectiveness of Various Potential Predictors of Response to Treatment With SSRIs in Patients With Depressive Disorder.},
  author={Martin Bares and Tomas Novak and Martin Brunovsk{\'y} and Miloslav Kopecek and Cyril H{\"o}schl},
  journal={The Journal of nervous and mental disease},
  year={2017},
  volume={205 8},
  pages={
          618-626
        }
}
The substantial non-response rate in depressive patients indicates a continuing need to identify predictors of treatment outcome. The aim of this 6-week, open-label study was (1) to compare the efficacy of a priori defined predictors: ≥20% reduction in MADRS score at week 1, ≥20% reduction in MADRS score at week 2 (RM ≥ 20% W2), decrease of cordance (RC), and increase of serum and plasma level of brain-derived neurotrophic factor at week 1; and (2) to assess whether their combination yields… CONTINUE READING
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