The Comparative Effects of Postoperative Analgesic Therapies on Pulmonary Outcome: Cumulative Meta-Analyses of Randomized, Controlled Trials

@article{Ballantyne1998TheCE,
  title={The Comparative Effects of Postoperative Analgesic Therapies on Pulmonary Outcome: Cumulative Meta-Analyses of Randomized, Controlled Trials},
  author={Jane C. Ballantyne and Daniel B Carr and Sarah D. deFerranti and Thomas Suarez and Joseph Lau and Thomas C. Chalmers and Italo Francesco Angelillo and Frederick Mosteller},
  journal={Anesthesia \& Analgesia},
  year={1998},
  volume={86},
  pages={598-612.}
}
We performed meta-analyses of randomized, control trials to assess the effects of seven analgesic therapies on postoperative pulmonary function after a variety of procedures: epidural opioid, epidural local anesthetic, epidural opioid with local anesthetic, thoracic versus lumbar epidural opioid, intercostal nerve block, wound infiltration with local anesthetic, and intrapleural local anesthetic. Measures of forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC), vital capacity (VC… Expand
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Morphine by intravenous infusion provided comparable pain relief to intermittent intramuscular morphine; there was no significant difference in the incidence of postoperative pulmonary complications. Expand
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The Comparative Effects of Postoperative Analgesic Therapies on Pulmonary Outcome
TLDR
Meta-analyses of randomized, control trials to assess the effects of seven analgesic therapies on postoperative pulmonary function after a variety of procedures found that epidural opioid, epidural local anesthetic, and thoracic versus lumbar epidural opioids influence pulmonary function. Expand
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Epidural analgesia with a combination of local anesthetic and opioid improves patient comfort, however, this type of analgesia does not decrease the incidence of postoperative pulmonary complications, does not reduce the length of the hospital stay, and carries the risk of complications from episodic systemic hypotension. Expand
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It is concluded that thoracic epidural morphine administration in patients after thoracotomy results in decreased morphine requirements and the same degree of analgesia as does lumbar administration. Expand
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The technique of continuous intercostal nerve block described in this study is an effective treatment for the control of post-thoracotomy pain and did lead to systemic accumulation. Expand
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