The Combination of MBP and BCG-Induced Dendritic Cell Maturation through TLR2/TLR4 Promotes Th1 Activation In Vitro and Vivo

Abstract

To explore whether TLR2/TLR4 could be involved in the maturation of dendritic cells and polarization of CD4+ T cells induced by dendritic cells stimulated with MBP and BCG, in vitro and in vivo experiments using TLR2-/- or TLR4-/- mice were employed. MBP and BCG elevated CD80, CD86 and MHC class II expressed on dendritic cells and increased IL-12 protein… (More)
DOI: 10.1155/2017/1953680

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@inproceedings{Jiang2017TheCO, title={The Combination of MBP and BCG-Induced Dendritic Cell Maturation through TLR2/TLR4 Promotes Th1 Activation In Vitro and Vivo}, author={Lina Jiang and Guomu Liu and Weihua Ni and Nannan Zhang and Jing Jie and Fei Xie and GuiXiang Tai}, booktitle={Mediators of inflammation}, year={2017} }