The Collaborative Study on the Genetics of Alcoholism

  title={The Collaborative Study on the Genetics of Alcoholism},
  author={Victor M Hesselbrock and Henri Begleiter and Bernice Porjesz and Sean J. O'Connor and Lance O Bauer},
  journal={Alcohol Health and Research World},
  pages={228 - 236}
There is substantial information supporting the role of genetic factors in the susceptibility for alcohol dependence. However, the identification of specific genes that contribute to this predisposition has proven elusive, although several theoretically relevant candidates, e.g. DRD2 or 5-HT1B, have been considered. The difficulty in identifying specific genes may be related to the clinical heterogeneity of the disorder resulting in a poorly defined phenotype for genetic analysis. An… 

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