The Coevolution of Genes and Genetic Codes: Crick’s Frozen Accident Revisited

@article{Sella2004TheCO,
  title={The Coevolution of Genes and Genetic Codes: Crick’s Frozen Accident Revisited},
  author={G. Sella and D. Ardell},
  journal={Journal of Molecular Evolution},
  year={2004},
  volume={63},
  pages={297-313}
}
The standard genetic code is the nearly universal system for the translation of genes into proteins. The code exhibits two salient structural characteristics: it possesses a distinct organization that makes it extremely robust to errors in replication and translation, and it is highly redundant. The origin of these properties has intrigued researchers since the code was first discovered. One suggestion, which is the subject of this review, is that the code’s organization is the outcome of the… Expand
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