The Coagulation of Blood by Snake Venoms and Its Physiologic Significance

  title={The Coagulation of Blood by Snake Venoms and Its Physiologic Significance},
  author={Harry Eagle},
  journal={The Journal of Experimental Medicine},
  pages={613 - 639}
  • Harry Eagle
  • Published 1937 in The Journal of experimental medicine
Nine of the 17 venoms here tested were found capable of coagulating citrated blood or plasma. As has been believed by most workers in the field, 7 of these 9 coagulant venoms convert fibrinogen to an insoluble modification resembling fibrin (Bothrops atrox, Bothrops jararaca, Bothrops nummifera, Crotalus adamanteus, Crotalus horridus, Crotalus terrificus basiliscus, Crotalus terrificus terrificus). The optimum pH for this coagulation was determined for 3 of these, and was found in each case to… CONTINUE READING
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