The Clinical and Forensic Toxicology of Z-drugs

@article{Gunja2013TheCA,
  title={The Clinical and Forensic Toxicology of Z-drugs},
  author={Naren Gunja},
  journal={Journal of Medical Toxicology},
  year={2013},
  volume={9},
  pages={155-162}
}
  • N. Gunja
  • Published 13 February 2013
  • Medicine
  • Journal of Medical Toxicology
The Z-drugs zolpidem, zopiclone, and zaleplon were hailed as the innovative hypnotics of the new millennium, an improvement to traditional benzodiazepines in the management of insomnia. Increasing reports of adverse events including bizarre behavior and falls in the elderly have prompted calls for caution and regulation. Z-drugs have significant hypnotic effects by reducing sleep latency and improving sleep quality, though duration of sleep may not be significantly increased. Z-drugs exert… 
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References

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TLDR
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TLDR
Few clinically important interactions appear to have been reported in the literature with zaleplon, zolpidem and zopiclone, and the fact that these drugs are newer to the market and have not been as extensively studied as the conventional benzodiazepines may be the reason for this.
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TLDR
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TLDR
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TLDR
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TLDR
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Flumazenil antagonizes the central effects of zolpidem, an imidazopyridine hypnotic
TLDR
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