The Clinical Significance of Thymidine Kinase 1 Measurement in Serum of Breast Cancer Patients Using Anti-TK1 Antibody

@article{He2000TheCS,
  title={The Clinical Significance of Thymidine Kinase 1 Measurement in Serum of Breast Cancer Patients Using Anti-TK1 Antibody},
  author={Q. He and Li Zou and Pan Zhang and Jin Lui and Sven Skog and Tommy Fornander},
  journal={The International Journal of Biological Markers},
  year={2000},
  volume={15},
  pages={139 - 146}
}
  • Q. He, L. Zou, T. Fornander
  • Published 1 April 2000
  • Medicine, Biology
  • The International Journal of Biological Markers
The activity of total thymidine kinase in serum (S-TK) has been used as a tumor maker for decades. To date such activity has been determined using [125]I-iodo-deoxyuridine as a substrate. The aim of this study was to develop a new, antibody-based technique for the measurement of cytoplasmic thymidine kinase (TK1) in serum. Both mono- and polyclonal antibodies against S-TK1 were used in dot blot assay. S-TK1 was characterized by SDS and IEF techniques. Sixty-five breast cancer patients were… 

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TLDR
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TLDR
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TLDR
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