The Clinical Relevance of Low-Density-Lipoproteins Size Modulation by Statins

  title={The Clinical Relevance of Low-Density-Lipoproteins Size Modulation by Statins},
  author={Manfredi Rizzo and Kaspar Berneis},
  journal={Cardiovascular Drugs and Therapy},
The predominance of small, dense low density lipoproteins (LDL) has been accepted as an emerging cardiovascular risk factor by the National Cholesterol Education Program Adult Treatment Panel III; in fact, LDL size seems to be an important predictor of cardiovascular events and progression of coronary heart disease. Several studies have also shown that the therapeutical modulation of LDL size is of great benefit in reducing the risk of cardiovascular events. Hypolipidemic treatment is able to… CONTINUE READING


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