The Clinical Neuropsychiatry of Multiple Sclerosis

  title={The Clinical Neuropsychiatry of Multiple Sclerosis},
  author={Anthony Feinstein},
  journal={CNS Spectrums},
  pages={362 - 362}
Multiple sclerosis (MS) is the most common cause of neurological disability in young and middle-aged adults. Although Charcot noted behavioral changes associated with MS, nearly a century would elapse before researchers began defining their full extent and severity. Broadly speaking, abnormalities may be divided into those of mood and cognition. Many patients are afflicted with both and it is essential that clinicians are not only aware of this but understand how to detect problems and provide… 
1 Citations
Arbutin Improves Functional Recovery and Attenuates Glial Activation in Lysolecethin-Induced Demyelination Model in Rat Optic Chiasm
It is demonstrated that arbutin improves functional recovery and myelin repair in the demyelinated optic chiasm through attenuation of inflammation, astrocyte activation, and oxidative stress.


Affective disorders in multiple sclerosis. Review and recommendations for clinical research.
English-language studies of euphoria, pathological laughing and weeping, depression, and bipolar disorder are presented, methodological limitations are described, and areas for future clinical research are suggested.
An examination of suicidal intent in patients with multiple sclerosis
Suicidal intent, a potential harbinger for suicide, is common in MS and is strongly associated with major depression, alcohol abuse, and social isolation.
Cognitive dysfunction in multiple sclerosis . II . Impact on employment and social functioning
  • Neurology .
  • 1991
The Clinical Newopsycniatry of Multiple Sclerosis
  • 1989