The Clearance of Mannitol and Erythritol In Rat Bile.∗

  title={The Clearance of Mannitol and Erythritol In Rat Bile.∗},
  author={E. L. Forker and T. Hicklin and H. Sornson},
  journal={Proceedings of the Society for Experimental Biology and Medicine},
  pages={115 - 119}
  • E. L. Forker, T. Hicklin, H. Sornson
  • Published 1967
  • Chemistry, Medicine
  • Proceedings of the Society for Experimental Biology and Medicine
  • Summary In the rat, as in the guinea pig, dehydrocholate choleresis leads to increased excretion of mannitol and erythritol, but in the rat the amounts of the solutes appearing in bile are greater. This difference is much more pronounced for the larger solute, mannitol. For mannitol, but not for erythritol, the rate of change of clearance following dehydrocholate is also greater in the rat. Unlike its effect in the guinea pig, secretin produces only a trivial choleresis in the rat. Despite a… CONTINUE READING
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