The Class II cytokine receptor (CRF2) family: overview and patterns of receptor-ligand interactions.

@article{Langer2004TheCI,
  title={The Class II cytokine receptor (CRF2) family: overview and patterns of receptor-ligand interactions.},
  author={Jerome A. Langer and E Cali Cutrone and Sergei Kotenko},
  journal={Cytokine & growth factor reviews},
  year={2004},
  volume={15 1},
  pages={33-48}
}
Expanded genomic information has driven the discovery of new members of the human Class II family of cytokine receptors (CRF2), which now includes 12 proteins. The corresponding cytokines have been identified, paired with their receptors and initially characterized for function. These cytokines include: a new human Type I IFN, IFN-kappa; molecules related to IL-10 (IL-19, IL-20, IL-22, IL-24, IL-26); and IFN-lambdas (IL-28/29), which have antiviral and cell stimulatory activities reminiscent of… CONTINUE READING

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