The Cis-regulatory Logic of the Mammalian Photoreceptor Transcriptional Network

@article{Hsiau2007TheCL,
  title={The Cis-regulatory Logic of the Mammalian Photoreceptor Transcriptional Network},
  author={Timothy H.-C. Hsiau and Claudiu Diaconu and Connie A. Myers and Jongwoo Lee and Constance L. Cepko and Joseph C Corbo},
  journal={PLoS ONE},
  year={2007},
  volume={2},
  pages={191 - 212}
}
The photoreceptor cells of the retina are subject to a greater number of genetic diseases than any other cell type in the human body. The majority of more than 120 cloned human blindness genes are highly expressed in photoreceptors. In order to establish an integrative framework in which to understand these diseases, we have undertaken an experimental and computational analysis of the network controlled by the mammalian photoreceptor transcription factors, Crx, Nrl, and Nr2e3. Using microarray… CONTINUE READING
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