The Chronic Fatigue Syndrome: A Comprehensive Approach to Its Definition and Study

  title={The Chronic Fatigue Syndrome: A Comprehensive Approach to Its Definition and Study},
  author={K. Fukuda and S. Straus and I. Hickie and M. Sharpe and J. Dobbins and A. Komaroff},
  journal={Annals of Internal Medicine},
  • K. Fukuda, S. Straus, +3 authors A. Komaroff
  • Published 1994
  • Medicine
  • Annals of Internal Medicine
  • We have developed a conceptual framework and a set of research guidelines for use in studies of the chronic fatigue syndrome. The guidelines cover the clinical and laboratory evaluation of persons with unexplained fatigue; the identification of underlying conditions that may explain the presence of chronic fatigue; revised criteria for defining cases of the chronic fatigue syndrome; and a strategy for dividing the chronic fatigue syndrome and other unexplained cases of chronic fatigue into… CONTINUE READING
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    Publications referenced by this paper.
    Chronic fatigue syndrome: a working case definition.
    • 1,608
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    Development of a fatigue scale.
    • 1,946
    • PDF