The Chronic Fatigue Syndrome: A Comprehensive Approach to Its Definition and Study

@article{Fukuda1994TheCF,
  title={The Chronic Fatigue Syndrome: A Comprehensive Approach to Its Definition and Study},
  author={Keiji Fukuda and Stephen E. Straus and Ian B. Hickie and Michael Sharpe and James Goodman Dobbins and Anthony L. Komaroff},
  journal={Annals of Internal Medicine},
  year={1994},
  volume={121},
  pages={953-959}
}
We have developed a conceptual framework and a set of research guidelines for use in studies of the chronic fatigue syndrome. The guidelines cover the clinical and laboratory evaluation of persons with unexplained fatigue; the identification of underlying conditions that may explain the presence of chronic fatigue; revised criteria for defining cases of the chronic fatigue syndrome; and a strategy for dividing the chronic fatigue syndrome and other unexplained cases of chronic fatigue into… 
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