• DOI:10.7326/0003-4819-121-12-199412150-00009
Corpus ID: 510735

The Chronic Fatigue Syndrome: A Comprehensive Approach to Its Definition and Study

@article{Fukuda1994TheCF,
  title={The Chronic Fatigue Syndrome: A Comprehensive Approach to Its Definition and Study},
  author={K. Fukuda and S. Straus and I. Hickie and M. Sharpe and J. Dobbins and A. Komaroff},
  journal={Annals of Internal Medicine},
  year={1994},
  volume={121},
  pages={953-959}
}

• K. Fukuda, S. Straus, +3 authors A. Komaroff
• Published 1994
• Medicine
• Annals of Internal Medicine

We have developed a conceptual framework and a set of research guidelines for use in studies of the chronic fatigue syndrome. The guidelines cover the clinical and laboratory evaluation of persons with unexplained fatigue; the identification of underlying conditions that may explain the presence of chronic fatigue; revised criteria for defining cases of the chronic fatigue syndrome; and a strategy for dividing the chronic fatigue syndrome and other unexplained cases of chronic fatigue into… Expand